Apigenin

Nov 2020 -The Therapeutic Potential of Apigenin - The beneficial indications are reported and discussed in detail, including effects in diabetes, amnesia and Alzheimer’s disease, depression and insomnia, cancer, etc.

Roc takes 4.2 mg apigenin twice a day in Mito-C. Apigenin is a common dietary flavonoid that is abundantly present in many fruits, vegetables and Chinese medicinal herbs and serves multiple physiological functions, such as strong anti-inflammatory, antioxidant, antibacterial and antiviral activities and blood pressure reduction. Therefore, apigenin has been used as a traditional medicine for centuries. Recently, apigenin has been widely investigated for its anti-cancer activities and low toxicity. Apigenin [20], mimics the metabolic pathway effect of caloric restriction.  It inhibits CD 38, also known as cyclic ADP ribose hydrolase, a glycoprotein found on the surface of many immune cells. Apigenin restores NAD+ toward more youthful levels.  It also induces cancer cell apoptosis or autophagy and attenuates cancer cell proliferation or metastasis [30].