GRG BO choices
My wife (A) and I take 100mg of Desatanib, 1 gm of Quercetin, 1 gm of Fisetin and 500mg of Azithromycin one time quarterly. We were taking the same dosage monthly but changed to Quarterly a year ago to reduce the cost of Desatanib. No side effects. I'm not a biologist and can only rely on what I read, and at 86 I certainly have a lot of senescent cells to eliminate. For simplicity, I combine the most common anti-senescent products into a periodic treatment protocol that began as a monthly treatment and now a once every three months treatment. Below is an article re. Azithromycin. Some have implied that the different anti-senolytic products may target different tissues - hence my combination protocol. Antibiotics eliminate senescent cells associated with ageing (medicalxpress.com)
FULL RECIPE OF SUPPLEMENTS:
Prescription Medicine:
Nexium - - 40mg 2x daily (GERD)
Celebrex - - 100 mg 2x daily (Arthritis pain)
Lipitor - - 10mg each evening (Maintain low cholesterol)
Jalyn 0.5 – 0.4 each evening (Control BPH, relax sphincter) Started 2017
Carafate - - 1gm 4x each night (Protect from GERD)
Cytotec - - 100mcg 2x each night (Protect from GERD)
Retin A, 1% - - Apply every other evening (Clear skin)
Aspirin - - 162 mg once daily (Thin blood)
Metformin - - 2 gm daily (Control slightly high A1c)
Synthroid - - 75 mcg daily (Boost sluggish thyroid)
Toprol 12.5 mg daily (Maintain low blood pressure)
Vitamins, Herbals, Supplements:
Life Extension Foundation (LEF) mix (see separate sheet) at least 30 years
LEF Booster (oil soluble vitamins)
LEF Cognitive mix
D3 – 10,000 IU daily (plus in LEF mix)
DHEA – 25mg daily
Curcumin – 400mg daily
A.L-Carnitine – 1,200mg daily
Melatonin – 10mg nightly
B12, sublingual – 5mg daily
COQ10 – 200mg daily
Omega 3 – EPA: 700mg; DHA: 500mg
Magnesium – 144mg daily (plus in LEF Mix)
Carnosine – 1gm daily
Resveratrol – 250mg daily
Extracts: Blueberry, Grape, Pomegranate, Cruciferous Veg, Provinal, ++
Creatine – 3gm daily
Fiber supplement– 6gm daily
NAD+ booster (Niagen) 500mg daily (Nicotinamide Riboside) Started 2015
Acidophilus every morning
Reishi mushroom 980mg daily
ALT711 – 100 mg daily (anti-fibrotic)
Green tea extract 725mg daily
GABA 750mg daily
HMB 1gm daily
Gotu Kola 950mg daily (started mid 2019)
Rapamycin 5.0 mg once weekly with grapefruit juice - Started 2015 - MTOR C1 inhibitor
Senolytics cocktail quarterly
Desatanib 100mg, Started 2016
Quercetin 1 gm – started 2016
Azithromycin 500mg – started 2018
Fisetin – 1 gm 09/15/2018
Chronological age: 85
MyDNAge test 2018: Blood Age 74 (Urine age 70) Teloyears: Age 66
MyDNAge test 2019: Blood Age 75 (Urine age 71) Teloyears: Age 77
MyDNAge test 2020: Blood Age 75 (Urine age 72) Teloyears: Age 58
(Health good, light gym weekly, married, low stress)