Urolithin A - Ellagic acid

Nutrition Investigator now takes 500 mg in the morning. The supplement is a pomegranite extract. Dietary sources of urolithin A include pomegranate, strawberries, blackberries, walnuts, chestnuts, pistachios, and brewed tea, which contain ellagic acid and/or ellagitannins. Urolithin A is a natural food metabolite of the gut microbiome that has been shown to stimulate mitophagy and improve muscle function in aged animals and in models of muscular dystrophy, while also being safe, bioavailable, and able to induce mitochondrial gene expression in older adults. Experimental models consistently show that UA increases mitophagy and mitochondrial function and blunts excessive inflammatory responses. UA increased biomarkers of mitochondrial function in preclinical models of aging and in healthy elderly people