Osteocalcin

While diet is important, the key to anti-ageing lies in our bones. Osteocalcin, a hormone produced in the bones, could one day provide treatments for age-related issues such as muscle and memory loss. Scientists have also found that for humans, one way of naturally maintaining the levels of this hormone in the blood, even as we age, is through exercise, something that makes intuitive sense, as physical activity has long been known to have anti-ageing properties.  Exercise produces osteocalcin. Physical exercise seems universally beneficial to human and animal health, slowing cognitive aging and neurodegeneration. Exercise conditioned plasma dampens inflammation via clusterin and boosts memory. Blood borne factors transfer beneficial effects of exercise on neurogenesis and cognition to the aged brain