220115notes   

 

SUBJ: coffee for long life

SUBtitle: E O Wilson tribute

E O Wilson Tribute, father of sociobiology and so much more, written by our former student, Mark Moffett:

https://www.skeptic.com/reading_room/remembering-edward-wilson-1929-2021-tribute-by-mark-moffett/

See past newsletters here   

SHORT NO TES: individuals who drank lots of coffee (>6 cups/day) lived substantially longer; Vitamin D supplementation has long-term preventive effects on multiple chronic diseases like Alzheimer's disease, hypertension, schizophrenia, and type 2 diabetes; Vitamin D supplementation counteracted the winter decline in vitamin D and the increase in LDL cholesterol in 6-8 yr olds; Laser enucleation of the prostate is an effective and safe procedure in elderly patients; Cheese Ingestion Increases Muscle Protein Synthesis ; exercise prevented high-carbohydrate meal induced hyperglycemia; for joint pain: vitamin D, turmeric, borage oil, SAMe, avocado and soybeans, etc., Superfoods to fight cancer- 1. Pulses (beans, peas, lentils) 3. Mushrooms 4. Walnuts 5. Oatmeal 6. Berries 7. Tomatoes; A Green-MED, high-polyphenol diet low in red/processed meat is potentially neuroprotective for age-related brain atrophy; zinc deficiency esp. in older people promotes the flourishing of certain pathogenic taxa of the gut microbiome;  findings do not support the use of a single dose of 200 000 IU of vitamin D3, for moderate to severe COVID-19; Aduhelm (Aducanumab) from Biogen treatment may remove beta-amyloid from the brain.  

LONG NOTES: A study on coffee consumption was completed using the UK Biobank database. It revealed that coffee drinkers were 21% less likely to develop chronic liver disease, 20% less likely to develop chronic or fatty liver disease, and 49% less likely to die from chronic liver disease than non-coffee drinkers [NOTE: The number of AA members who were part of this cohort was not reported. For all of the non-AA members, coffee is the ubiquitous, ever-present, and copiously consumed beverage of first choice  ]. Second, the Journal of the American Heart Association reported that drinking one or more cups of caffeinated coffee a day [Who would ever consider de-caffeinated anyway?] revealed a lower risk of heart failure. Third, a report in PLOS Medicine revealed that individuals who drank 2 – 3 cups of coffee a day, 3 – 5 cups of tea a day, or a combination of 4 – 6 cups of coffee and tea had a 28% lower risk of dementia than the non-consumers. So, I’m sticking with coffee…lots of it!! To top it off, there was a big study in the United Kingdom that found those individuals who drank lots of coffee (>6 cups/day) lived substantially longer. treatment is controversial and effectiveness is being disputed.
The results indicated that vitamin D supplementation is a promising strategy with long-term preventive effects on multiple chronic diseases like Alzheimer's disease, hypertension, schizophrenia, and type 2 diabetes

 and thus has the potential to decrease all-cause mortality. However, the current vitamin D supplementation strategy might not be an efficient intervention approach for these diseases, suggesting that new strategies are highly needed to improve the intervention outcomes.

Laser enucleation of the prostate is an effective and safe procedure in elderly patients, resulting in good functional outcomes, low morbidity, and few perioperative complications.

Vitamin D supplementation counteracted the winter decline in 25-hydroxyvitamin D and the increase in LDL cholesterol observed with placebo IN 6-8-y-old children . Effects of high dairy protein intake and vitamin D supplementation on body composition and cardiometabolic markers in 6-8-y-old children—the D-pro trial

Cheese Ingestion Increases Muscle Protein Synthesis Rates Both at Rest and During Recovery from Exercise in Healthy, Young Males: A Randomized Parallel-group Trial.

Three isocaloric meals induced unique postprandial changes in clinical and metabolomic biomarkers, while exercise prevented high-carbohydrate meal induced hyperglycemia

AARP: for joint pain: chondroitin/glucosamine (works for 50% of people after 2 months), omega-3 (anti-inflammatory), Methylsulfonylmethane (MSM) This sulfuric compound is naturally present in fruits, vegetables, grains, animals, and humans. Sulfur helps your body make connective tissue. Taking 1,000 to 3,000 mg or more of this natural chemical every day may help with symptoms of knee osteoarthritis, such as pain and swelling, vitamin D, turmeric, borage oil, SAMe studies show SAMe can work as well as nonsteroidal anti-inflammatory medications (NSAIDs), such as ibuprofen and naproxen, to reduce inflammation and relieve pain, boswellia can slow down cartilage loss, cats claw contains chemicals called tannins and sterols that may soothe inflammation. Studies show it might help with knee pain in osteoarthritis without side effects, avocado and soybeans,

 AARP: Superfoods to fight cancer- 1. Pulses (beans, peas, lentils) 3. Mushrooms 4. Walnuts 5. Oatmeal 6. Berries 7. Tomatoes

A Green-MED, high-polyphenol diet, rich in Mankai, green tea and walnuts and low in red/processed meat is potentially neuroprotective for age-related brain atrophy.

Rebalancing the unbalanced aged immune system – A special focus on zinc

-zinc deficiency esp. in older people promotes the flourishing of certain pathogenic taxa of the gut microbiome and how zinc supply counteracts such alterations in a manner that may contribute to longevity. 

The findings do not support the use of a single dose of 200 000 IU of vitamin D3, compared to placebo, for the improvement of cytokines, chemokines, and growth factor in hospitalized patients with moderate to severe COVID-19. 

First Israeli to receive new Alzheimer’s treatment. (TY WIN) Yirmiyahu Kozari, 57, recently diagnosed with Alzheimer’s disease, is the first Israeli to receive Aduhelm (Aducanumab) from Biogen, at the Tel Aviv Sourasky Medical Center. The treatment removes beta-amyloid from the brain. This is controversial and may not work.

A happy song  Don’t let the old man in