Feb 27, 2021 Newsletter
Photo: 210227 meditatinginoffice
SUBJ: Longer healthier lives forecast soon; Strengthen your immune system; Roc meditates
SHORT NOTES: the Economist Feb 6th, “Ageing can be cured, it will be very soon.” Roc note: It does not need to be cured, just kept healthy; In the past year or so we have had about 500,000 deaths from Covid-19 in the US. Cigarette smoking is responsible for 4,800,000!! An estimated 300,000 deaths per year are due to the obesity epidemic. 72% of Americans are overweight or obese; Currently, there are five prescription drugs available for Alzheimer’s symptom management; For weight loss, consider IGOB131, a seed extract nutritional supplement; Can We Cure Aging? - Recent results from the Mayo Clinic suggest that many symptoms of aging result from the accumulation of senescent cells; 13 Tips to Strengthen Your Immune System
LONG NOTES:
Ageless, reviewed in the Economist Feb 6th, states “Ageing can be cured, it will be very soon.” Roc note: It does not need to be cured, just kept healthy; In the past year or so we have had about 500,000 deaths from Covid-19 in the US. Cigarette smoking is responsible for 4,800,000!! An estimated 300,000 deaths per year are due to the obesity epidemic. 72% of Americans are overweight or obese.
Currently, there are five prescription drugs available for Alzheimer’s symptom
management. These drugs can help improve the quality of life of individuals living with the disease, as well as the lives of their caregivers. A drug developed by the pharmaceutical company Eli Lilly successfully cleared the toxic plaques of amyloid protein that gum up the brain in persons with Alzheimer’s disease.
For weight loss, consider IGOB131. 2009- IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation either 150 mg of IGOB131 or matching placebo in a double blinded fashion, 30–60 minutes before lunch and dinner. At baseline, 4, 8 and 10 weeks of the study. Exptl went from 98 to 85 kg over 10 weeks. 2020 in rats - Overall, both the in vitro and in vivo findings indicate that IGESE may be a promising prophylactic cardioprotective agent against DOX-induced cardiotoxicity, at least in part mediated via IGESE's antioxidant and free radical scavenging and antithrombotic mechanisms. 2013 - Two RCTs reported adverse events including headache, sleep difficulties, and flatulence. There were no significant differences between Irvingia gabonensis and placebo for adverse events. Until good quality trials were available that demonstrate its efficacy, Irvingia gabonensis could not be recommended as a weight loss aid. Efforts were made to find published and unpublished studies, which minimised the risk of publication bias. From Memorial Sloan Kettering: Preliminary studies suggest that the bark of African mango has antimicrobial (1), analgesic (2), and anthelmintic (12) effects. Its seed is rich in fiber and may help slow gastric emptying which results in gradual absorption of sugar, thereby decreasing the rise in blood glucose level in diabetics after eating (3). The seed extract showed positive effects in controlling obesity and lowering cholesterol levels (4). However, most studies conducted on African mango have been small with poor methodology (13) (14) (15). Larger clinical trials are needed to examine the safety and benefits of this fruit extract as a weight loss supplement.
Can We Cure Aging? - Recent results from the Mayo Clinic suggest that many symptoms of aging result from the accumulation of senescent cells, and that many aging effects can be reversed by causing senescent cells expressing the protein p16 to "self-destruct". A new company, Oisin Biotechnology, has developed a plasmid-based DNA technique using this approach that clears senescent cells from animals and humans, offering the possibility of a general treatment for aging.
13 Tips to Strengthen Your Immune System